Research Article

Seroprevalence of Rubella Virus Among Pregnant Women Attending Antenatal Clinic at Aminu Kano Teaching Hospital, Kano State, Nigeria

1 Department of Medical Microbiology and Parasitology, Faculty of Clinical Science, College of Health Science, Bayero University, Kano, Nigeria
2 Department of Medical Microbiology and Parasitology, Faculty of Clinical Sciences, Bayero University Kano, P.M.B. 3011.
3 Department of Medical Microbiology and Parasitology, Faculty of Clinical Science, Bayero University Kano, Nigeria
4 Department of Community Medicine, Faculty of Clinical Science, College of Health Science, Bayero University, Kano, Nigeria
5 Department of Microbiology and Parasitology, Aminu Kano Teaching Hospital Kano, Nigeria
* Corresponding author: drymohd@yahoo.com
Published: Dec, 2020
Pages: 5375-5380

Abstract

Rubella is an acute infectious disease caused by rubella virus (RUBV). Rubella virus infection remains one of the major global public health problems, especially in developing countries causing 100 000 cases of congenital rubella syndrome (CRS) every year. However, data on this subject matter is scarce in the study area. This study was aimed at determining the seroprevalence of rubella virus among pregnant women attending antenatal clinic at Aminu Kano Teaching Hospital, Kano State. It was a descriptive, cross sectional and hospital based study. A total of 276 pregnant women participated in the study. Information on bio-data, socio-demographic characteristics and medical history of the participants and risk factors were obtained via a structured questionnaire and hospital records. Blood samples were analysed for RUBV IgG and IgM antibody using ELISA method. The data generated were analysed using SPSS for window version 20.0. An overall rubella IgM prevalence of 32.25% was obtained in the study. Two (0.73%) participants were positive to only rubella IgM antibody, 58.33% to only rubella IgG antibody and 31.52% to both IgM and IgG antibodies. The result of the study showed that there was no statistical relationship between the tested socio-demographical parameters and reproductive characters. Rubella virus incidence among pregnant women in this study area was high; this indicates the need for public enlightenment campaign on possible mode of prevention and control to limit the spread of the disease and its associated morbidity and mortality.

References

  1. Adewumi, O.M., Oluseye, A.O., Babatunde, A.O., Temitope, O.C.F., Waidi, F.S., Olubukola, A. (2015). Epidemiological Evaluation of Rubella virus infection among pregnant women in Ibadan Nigeria. African Journal of Immunoassay and Immunochemistry, 36(6):613-621.
  2. Adewumi, O.M., Olasanya, R.B., Oladunjoye, B.A. and Adeniji, J.A. (2013). Rubella IgG Antibody Among Nigerian Pregnant Women Without Vaccination History. African Journal of Clinical and Experimental Microbiology, 14(1):40-44.
  3. Bigwan, I.E.Zanyu, E.D., Pam, B.B., Monday, D. (2013). Seroepidemiology of rubella IgG among unvaccinated pregnant women attending antenatal clinics in two rural communities in Plateau State, Nigeria. European Journal of Preventive Medicine, 1(3): 58-62.
  4. Bouthry, E., Picone, O., Hamdi, G., Grangeot-Keros, L., Ayoubi, J. and Vauloup-Fellous, C. (2014). Rubella and pregnancy: diagnosis, management and outcomes. Prenatal Diagnosis, 34:1246 – 1253.
  5. Chukwuedo, A.A., Chollom, S.C. and Salihu, A.E. (2016). Serological Investigation of Rubella IgG Antibodies among Pregnant Women Attending Antenatal Clinics in Abakaliki, Ebonyi State, Nigeria. Umar Musa Yar'adua University Journal of Microbiology Research, 3(2):50 – 55.
  6. Rubella IgM and IgG Antibodies in Women of Childbearing Age in Benue State, Nigeria. Nigerian Journal of Microbiology. 30(1): 3378-3381.
  7. Gubio, A.B., Olonitola, S., Jattau, E., Mukhtar, M.S. (2015). Sero-Prevalence of Rubella virus among Pregnant Women in Kaduna State Nigeria. Online Journal of Public Health Informatics. 9(1):1947 – 2579.
  8. Koki, Y.A., Musa, D.W., Mukhtar, M.D., Musa, M.A., Adamu, S., Muhammad, B.B. (2014). Sero-Prevalence of Rubella Virus IgM Antibodies among Pregnant Women Attending Muhammadu Abdullahi Wase Specialist Hospital Kano. Communications in Applied Sciences, 2(1):141 – 148.
  9. Kolawole, O.M and Adekoye, O.H. (2017). Prevalence of Immunoglobulin G Sero-positivity among Pregnant Women in Ilorin, Kwara state, Nigeria. Nigerian Journal of Pure and Applied Sciences, 30(2): 3030 – 3036.
  10. Mangga, H.K., Aminu, M. and Isa, M.A. (2017). Seroprevalence of Rubella among Pregnant Women Attending Ante-Natal Clinics in Kaduna Metropolis, Kaduna State, Nigeria. World Journal of Pharmaceutical Research, 6(12):730 – 735.
  11. National Bureau of Statistics (NBS) (2018). The latest population figures from National Bureau of Statistics you need to see; Business Insider by Pulse. Retrieved on 15th December, 2019.
  12. Okonko, B.J., Okonko, I.O, Makinde, T. S, Ogbu, O. (2019). Prevalence of rubella virus IgM antibodies among pregnant women in Rivers State, Nigeria. Trends Applied Sciences Research, 14(4): 288 – 295.
  13. Olajide O.M, Aminu M and Randawa A. and Adejo, S.O. (2015). Rubella-Specific IgM and IgG Antibodies Among Pregnant Women Seen In A Tertiary Hospital In Nigeria. International Journal of Women's Health, 7:75–83.
  14. Onyeukwu, E.U., Ogbonnaya, O., Oseni, O.M, Anyigor, E.P, Elom, E.O. and Ethel, N.N. (2019). Seroprevalence
  15. Oyinloye, S.O, Amama, C.A., Daniel, R., Ajayi, B.B., and Lawan, M.A. (2014). Seroprevalence Survey Of Rubella Antibodies Among Pregnant Women in Maiduguri, Borno State, Nigeria. African Journal of Clinical and Experimental Microbiology, 15(3):151-157.
  16. Priyanka, D., Ganesh, V., Anupriya, A., Uma, A. and Kalamani, S.M. (2017). Seroprevalence of Rubella among Asymptomatic Pregnant Women in A Rural Teaching Hospital Tamil Nadu. International Journal of Medical and Microbiology Research. 1(1): 7 – 12.
  17. Taku, N.A, Ndze, V.N, Abernathy, E., Hao, L., Waku-Kouomou, D., Icenogle, J.P, Wanji, S. and Akracheru, J.K.T. (2019). Seroprevalence of rubella virus antibodies among pregnant women in the Center and South-West regions of Cameroon. Public Library of Science, 14(11):1 – 10.
  18. Wondimeneha, Y., Tiruneha, M., Feredea, G., Aberab, B., Workinehc, M., Birhanied, M. and Tessemaa, B. (2018). Rubella virus infections and immune status among pregnant women before the introduction of rubella vaccine in Amhara Region State, Ethiopia. International Journal of Infectious Diseases, 76: 14 – 22.
  19. Yahaya, H, Ibrahim, A., Muhammad, A.B and Dandawaki, S.M. (2015). Sero-Prevalence Survey of Rubella IgM Antibodies among Pregnant Women in Kano, Nigeria. International Journal of Life Science and Engineering, 1(2): 56 – 61.
  20. Zanga, J, Mbanzulu, M.K., Kabasele, A.F., Ngatu, N.R, Numba, D.R. (2017). Rubella Seroprevalence and real-time PCR detection of RUBV among Congolese pregnant women. BMC Infectious Diseases.17: 250 – 257.
How to Cite

Y, R. M., Y., M., O, A. A., M, I. A., A, U. A., A.M, I., & M, A. (2020). Seroprevalence of Rubella Virus Among Pregnant Women Attending Antenatal Clinic at Aminu Kano Teaching Hospital, Kano State, Nigeria. Nigerian Journal of Microbiology, 34(2), 5375-5380. https://doi.org/10.67614/njm.2020.y08tkvif

R. M. Y, M. Y., A. A. O, I. A. M, U. A. A, I. A.M, and A. M, "Seroprevalence of Rubella Virus Among Pregnant Women Attending Antenatal Clinic at Aminu Kano Teaching Hospital, Kano State, Nigeria," Nigerian Journal of Microbiology, vol. 34, no. 2, pp. 5375-5380, December 2020. doi: 10.67614/njm.2020.y08tkvif

Share this article:
Facebook X / Twitter LinkedIn