Research Article

The In-vitro Antimicrobial Activity of Chlorella vulgaris Extracts on Selected Clinical Isolates

Agwa, O. K.1*, Egbo, S. 1.1, Uyo, O.C1
1 Department of Microbiology, Faculty of Science, University of Port Harcourt, P.M.B 5323 Port-Hatcourt. Rivers State, Nigeria.
* Corresponding author: obioma.agwa@uniport.edu.ng
Published: Jun, 2018
DOI: 10.67614/njm.2018.zi2m1hpt
Pages: 4104-4111

Abstract

The antifungal and antibacterial activities of extracts Chlorella vulgaris was studied by using methanol, ethanol, chloroform, acetone, hot aqueous and cold aqueous extracts on; Staphylococcus aureus, Klebsiella sp., Pseudomonas sp., Bacillus sp., Aspergillus niger, Aspergillus fumigatus, Candida sp. and Penicillium sp. The well in-agar and disc diffusion techniques adopted showed inhibitory effect with varying degree of susceptibility except cold aqueous extract which had no activity on any of the isolates used in the study. The highest zone of inhibition for bacterial isolates was observed in ethanol extract (6mm) for Klebsiella sp., while the highest zone of inhibition for fungal isolates was seen in methanol extract (4.5mm) for Candida sp. Hot aqueous extract showed the least zone of inhibition (0.5mm). The algal extract showed more activity on the bacterial isolates than commercial antibiotics used, while the antifungal drugs are more active on the fungal isolates than the extract. The natural derivatives from this algal species may be useful in treating certain specific infections and diseases as well as limit the proliferation of some clinical strains with little or no side effect.

Keywords

Chlorella vulgaris isolates antimicrobial activities ethanol chloroform acetone methanol aqueous hot and aqueous cold.

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How to Cite

K., A. O., 1., E. S., & O.C, U. (2018). The In-vitro Antimicrobial Activity of Chlorella vulgaris Extracts on Selected Clinical Isolates. Nigerian Journal of Microbiology, 32(1), 4104-4111. https://doi.org/10.67614/njm.2018.zi2m1hpt

A. O. K., E. S. 1., and U. O.C, "The In-vitro Antimicrobial Activity of Chlorella vulgaris Extracts on Selected Clinical Isolates," Nigerian Journal of Microbiology, vol. 32, no. 1, pp. 4104-4111, June 2018. doi: 10.67614/njm.2018.zi2m1hpt

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