Abstract

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Antibiotic Susceptibility Profile of Bacterial Isolated from Wound Sepsis Patients was study. The study aimed at assessing the antibiotic susceptibility of some bacteria isolated from wound sepsis of patients attending Immanuel General Hospital Eket. Random sampling technique was employed in this study. One hundred (100) wound swabs were obtained and cultured on Blood agar and MacConkey agar. Most Bacterial isolates from the wound were susceptible to most of the antibiotics with few of them being resistant. The prevalence of bacteria isolated from wound swabs were Staphylococcus aureus (42.8%), Escherichia coli (14.3%), Pseudomonas aeruginosa (14.3%), Streptococcus pyogenes (11.4%), Klebsiella pneumoniae, (8.6%) and Proteus sp. (8.6%). The percentage susceptibility results showed that Staphylococcus aureus was highly susceptible to Rifampicin (96%), Streptomycin (92%) and Levofloxacin (88%). Streptococcus pyogenes, exhibited 100% susceptibility to Ciprofloxacin, Chloramphenicol and Levofloxacin but strongly resisted Amoxicillin (75%). Escherichia coli showed high susceptibility to Septrin (90%), Augmentin (90%), Tarivid (80%) and Nalidixic acid (70%). Pseudomonas aeruginosa and Proteus spp. isolates were resistant to Ciprofloxacin, Gentamycin. Klebsiella pneumoniae showed resistance to Ciprofloxacin (75%), Augmentin (75%) and Streptomycin (62%). The demographic factor; sex, age, occupation, area of domicile of patients was associated with the occurrence of bacteria from the wound sepsis. The frequency of single and multiple drug resistance is highly alarming and is a growing threat to the control of infectious diseases globally.

Keywords: Antibiotic, Susceptibility, Bacteria, Wound Sepsis