Abstract

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Measles account for nearly half of the 1.7 million annual deaths due to childhood vaccine-preventable diseases. Presence of measles specific IgG antibodies has been proven to correlate with protection (immunity) to natural measles infection. This study was therefore designed to determine the seroprevalence of measles specific IgG in relation to vaccination status, types of settlement and parents’ occupation among children aged 0-14 years in Adamawa State. The research was carried out within the three senatorial districts of the State. Three hundred and sixty eight (368) serum samples collected from children were used to determine the prevalence using ELISA technique. Questionnaire was used to obtain demographic data of the children. The study revealed that 227 (61.6%) of the children had protective measles IgG antibody, while 141 (38.4%) had unprotective or no measles IgG antibody. Statistical analysis revealed that there was significant association between prevalence of measles specific IgG antibody and vaccination status against measles, types of settlement and parents’ occupation (p-value < 0.05).

Keywords: Demographic data, ELISA, IgG Antibody, Measles virus, Prevalence, Vaccination,