Abstract

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This work was aimed at ascertaining the antifungal potency of some antifungal drugs on fungal isolates from barbering equipment. Two hundred (200) samples were collected from barbering equipment pre and post sterilization. Samples were inoculated onto Sabouraud Dextrose Agar and incubated at room temperature for 5 7days.Subcultures were carried out to purify the isolates. One hundred (100) isolates belonging to six (6) genera Trichophyton, Microsporum, Aspergillus, Rhizopus, Candida and Scedosporium were identified. Antifungal drugs fluconazole, ketoconazole, griseofulvin, itraconazole and nystatin of known concentrations were screened in vitro on the isolates using the Kirby-Bauer disc diffusion method. The isolates were resistant to fluconazole and griseofulvin. The Minimum Inhibitory Concentrations (MICs) of the effective drugs ranged from 0.15625 to lOmg/ml and Minimum Fungicidal Concentrations (MFCs) from 1.25 to >20mg/ml. Nystatin had different MIC and MFC values. The effective drugs exhibited little activities on the isolates proving their ineffectiveness in treatment

Keywords: antifungal drugs, fungal isolates, barbering equipment, MIC and MFC