Abstract

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A study to isolate and determine the antibiogram pattern of Staphylococcus saprophytics associated with asymptomatic bacteriuria in pregnant women was carried out. A total of ninety one (91) clinical urine samples were collected from antenatal women attending some hospitals in Bauchi metropolis. Out of these samples 32.9% (30 of 91) were positive with S. saprophytics for significant bacteriuria (CFU > 105/mL). The highest prevalence of 43.8% (14 of 32) was found among the age group of 26-30 years, with the least (0.0%) in 41-50 years. Most of the isolates were highly sensitive to Amikacin (73.3%), Gentamicin (63.3%), Cefotaxime (56.7%), Imipenem (86.7%), Ciprofloxacin (83.3%) and Nitrofurantoin (70.0%). Multidrug resistance to some beta-lactam drugs (Ampicillin and Amoxycillin) was observed. This study found low socioeconomic status, decreased level of education, increased maternal age and parity as risk factors that could raised the rate of ASB. The relatively high prevalence of the infection in pregnancy is alarming, and require urgent attention of clinicians as the organism remain significant among sexually active women

Keywords: Asymptomatic bacteriuria(ASB), Antenatal, Beta-lactam drugs, Multidrug resistance, Pregnant women. Staphylococcus saprophytics,