Abstract

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The antifungal and antibacterial activities of extracts Chlorella vulgaris was studied by using methanol, ethanol, chloroform, acetone, hot aqueous and cold aqueous extracts on; Staphylococcus aureus, Klebsiella sp., Pseudomonas sp., Bacillus sp., Aspergillus niger, Aspergillus fumigatus, Candida sp. and Penicillium sp. The well in-agar and disc diffusion techniques adopted showed inhibitory effect with varying degree of susceptibility except cold aqueous extract which had no activity on any of the isolates used in the study. The highest zone of inhibition for bacterial isolates was observed in ethanol extract (6mm) for Klebsiella sp., while the highest zone of inhibition for fungal isolates was seen in methanol extract (4.5mm) for Candida sp. Hot aqueous extract showed the least zone of inhibition (0.5mm). The algal extract showed more activity on the bacterial isolates than commercial antibiotics used, while the antifungal drugs are more active on the fungal isolates than the extract. The natural derivatives from this algal species may be useful in treating certain specific infections and diseases as well as limit the proliferation of some clinical strains with little or no side effect

Keywords: Chlorella vulgaris, isolates, antimicrobial activities, ethanol, chloroform, acetone, methanol, aqueous hot and aqueous cold.