Articles

Browse our published research articles

482 articles
191
Research Article DOI: 10.67614/njm.2020.5onyh6ix

Incidence of Fluoroquinolone and Multidrug Resistant Salmonella species in Intensively Reared Pigs and Chickens in Nsukka, Nigeria

Ugwuanyi, J. O.*, Chah, K. F, Ajibo, Q. C.

Fluoroquinolones are broad spectrum antimicrobial agents used to treat infections caused by microbial pathogens especially those resistant to other classes of antimicrobial drugs. The introduction of fluoroquinolones into veterinary therapy has been accompanied by an increase in resistance. Salmonella represents a challenge in modern animal production. This study determined the incidence of fl...

Jun, 2020 pp. 4863-4873
192
Research Article DOI: 10.67614/njm.2020.3n0ik5sz

Extended Spectrum Beta-Lactamase production, Biofilm Formation and Antibiotic Resistance in Clinical Isolates of Klebsiella pneumoniae

Aisha Shitu Sa'id*, Mukhkar, M. D, Bukar, A., Yusha’u, M

Klebsiella pneumoniae is an opportunistic pathogen frequently multidrug-resistant, responsible for both health care and community associated infections. The appearance of extended spectrum β- lactamase in addition to the biofilm-forming phenotype, is a major problem in the clinical environment. This study aimed to detect ESBL production, biofilm formation and antibiotic resistance profile of cl...

Jun, 2020 pp. 4874-4883
193
Research Article DOI: 10.67614/njm.2020.au4zncmm

Proximate Composition and Microbiological Analysis of Yaji (Spiced Pepper Mixture) Sold Within Kano Metropolis, Nigeria

Ruqayyah, A.U*, Latifat, A.

Food safety must be given high priority in any society. This study was aimed at assessing the proximate composition and microbiological quality of yaji. A total of nine different yaji were randomly purchased from retail stores within Kano metropolis while three samples were prepared in the laboratory as control. The result of the study revealed that the yaji samples studied had moisture content ra...

Jun, 2020 pp. 4884-4891
194
Research Article DOI: 10.67614/njm.2020.h2d6unrm

Assessment of HIV 1 GP120/CD4 Binding Inhibition Potential of Solanum nigrum Crude Fruit Extracts

Mohammed, B.*, Gali, S., Abba S.A., Jobbi, Y.D.

Human immunodeficiency virus (HIV) infection is still contributing significantly in morbidities and mortalities in the world today, more especially in developing countries. The drugs normally use to treat the infection are costly, toxic, and less effective due to resistance by HIV. In view of that an assessment of gp120-CD4 binding inhibition potential of Solanum nigrum crude fruit extracts was co...

Jun, 2020 pp. 4892-4903
195
Research Article DOI: 10.67614/njm.2020.3usq7stu

Multi-Drug Resistant Efflux Pumps among Clinical Isolates of Staphylococcus aureus

Agbakoba, N. R.*, Imouokhome, E. I., Ezeanya-Bakpa, C. C

Against the background of high level antimicrobial resistance observed in isolates of Staphylococcus aureus, this study was conducted to determine the prevalence of multidrug resistant (MDR) efflux pumps among clinical isolates from University of Benin Teaching Hospital, Benin city. A total of 198 clinical isolates of Staphylococcus aureus obtained from various clinical specimens were used for...

Jun, 2020 pp. 4904-4910
196
Research Article DOI: 10.67614/njm.2020.hfz93itk

In vitro Antibacterial activity of the Bark Extracts of Anogeissus leiocarpus on Some Bacterial Pathogens

Sale, M.*, Pukuma S. M, Hamza, F. A.

The use of plant parts and extracts in traditional medicine has proved to be a good lead for the discovery of a potential plant derived antimicrobial agent. To this end we conducted in vitro screening of aqueous and alcoholic extracts of the bark of Anogeissus leiocarpus for antibacterial activity against clinical isolates of Salmonella Typhi, Staphylococcus aureus, Pseudomonas aeruginosa, Shig...

Jun, 2020 pp. 4911-4919
197
Research Article DOI: 10.67614/njm.2020.qwaopwel

Production of Fermented Weaning Food from Digitaria exilis (Acha) using Lactic Acid Bacteria

Hwabejire, H. O.*, Wakil, Sherifah M, Akpoghelie P. O.

Several different methods have been used to formulate weaning food through blending of different cereal crops that are locally available. Considering the good prospects of the ready availability of Acha cereals, fermentation of malted Digitaria exilis (Acha) flour using single and combination of lactic acid bacteria to produce weaning food was carried out. One hundred grams of acha grains were ste...

Jun, 2020 pp. 4920-4935
198
Research Article DOI: 10.67614/njm.2020.gylabaq5

Hepatitis E Virus Infection among People Living With HIV/AIDS in Kano State, Nigeria

Aliyu, A. S.*, Mohammed, Y., Rogo, L. D.

Hepatitis E is an emerging viral disease causing acute hepatitis worldwide which may result into a chronic hepatitis especially in immunocompromised individuals. The study determined the prevalence of Hepatitis E Virus (HEV) among people living with Human Immunodeficiency Virus (HIV) infection in Kano State. One hundred and eighty (180) subjects were enrolled for the study and their sera were ...

Jun, 2020 pp. 4936-4944
199
Research Article DOI: 10.67614/njm.2020.kt47ahjo

Antibiotics Resistance in Haemolytic Bacterial pathogens from Hospital Wastewaters

Obuekwe, I. S*, Osariemen. P. O.

Burden of morbidities and mortalities originating from bacterial pathogens and antibiotics resistance is on the rise, and hospital wastewaters are possible reservoirs of these pathogens. Infectious diseases and antibiotic resistance from Hospital Wastewaters could be spread into the environment. This study aimed at isolation, identification and antibiotic susceptibility characterization of hem...

Jun, 2020 pp. 4945-4953
200
Research Article DOI: 10.67614/njm.2020.nugs72st

Prevalence of Hepatitis E Virus among Children Presenting with Diarrhea in Selected Hospitals in Kano Metropolis

Babaguba, A. S.*, Rogo, L. D., Mujtaba, D., Sarki, E., Shehu K. A., Ibrahim, A.

Hepatitis E Virus (HEV) is a spherical non-enveloped single-strand positive-sense RNA virus of the Hepevirus genus and the family Hepeviridae. Its infection is newly recognized serious threat to global public health and Africa has been reported to be among the most severely affected regions in the world, most likely due to poor sanitation and weak public health facilities. The aim of the study...

Jun, 2020 pp. 4954-4961