Prevalence of Dengue Virus Antibody among Residents of a Rural Community in Southwestern, Nigeria
1 Department of Microbiology, Federal University Oye-Ekiti, Ekiti State. Nigeria
2 Institute of Virology, Hannover Medical School, Hannover, Germany
3 Department of Microbiology, Federal University, Oye-Ekiti, Ekiti state, Nigeria
4 Department of Vaccinology and Immunotherapeutics, School of Public Health, University of Saskatchewan, Saskatoon, SK, Canada, S7N 5B4.
* Corresponding author: okororle@nsmjournal.org.ng
2 Institute of Virology, Hannover Medical School, Hannover, Germany
3 Department of Microbiology, Federal University, Oye-Ekiti, Ekiti state, Nigeria
4 Department of Vaccinology and Immunotherapeutics, School of Public Health, University of Saskatchewan, Saskatoon, SK, Canada, S7N 5B4.
* Corresponding author: okororle@nsmjournal.org.ng
Abstract
Dengue is an endemic mosquito borne viral disease which is sparingly considered during routine screening for agents of febrile illnesses in Nigeria even though it has been reported across major cities in the country. We investigated the prevalence of dengue virus infection among dwellers of a rural community in Osun State, Southwestern Nigeria. Whole blood samples were collected from consenting participants in Hospitals and clinics within the community and tested for DENV IgM antibody using an ELISA (Wkea Medical Supplies, Guanzou China) technique. Out of a total number of 120 serum samples screened, 57.50% tested positive for dengue IgM while 42.50% were negative. Female samples recorded highest positivity of 37.5% compared to males having 20%. There was a statistically significant difference in the prevalence of dengue IgM antibody by gender (X2= 8.89, df= 1, &p= 0.003). There exist a statistical association between dengue IgM antibody and length of stay in the community (p
Keywords
Dengue virus
ELISA
Rural Community
IgM Antibody
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How to Cite
E, O. L., A., O. S., M., U. O., & O., U. D. (2019). Prevalence of Dengue Virus Antibody among Residents of a Rural Community in Southwestern, Nigeria. Nigerian Journal of Microbiology, 33(1), 4512-4517. https://doi.org/10.67614/njm.2019.t2s9lc85
O. L. E, O. S. A., U. O. M., and U. D. O., "Prevalence of Dengue Virus Antibody among Residents of a Rural Community in Southwestern, Nigeria," Nigerian Journal of Microbiology, vol. 33, no. 1, pp. 4512-4517, June 2019. doi: 10.67614/njm.2019.t2s9lc85
